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Role of the Extracorporeal Membrane Oxygenation Discussion Questions

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In the least severe cases of respiratory distress due to COVID-19, simply increasing the amount of oxygen that is breathed (e.g., using an oxygen mask) can bring oxygen saturation levels back to normal. Describe how this treatment works in the context of partial pressure driven transfer of oxygen, oxygen-hemoglobin binding, and levels of blood oxygenation in COVID-19 patients compared to normal blood oxygenation levels. For the acute symptoms of Novel Coronavirus (COVID-19), the oxygen in blood may go down causing a shortness of breath to patients. Thus, supplying enough non-invasive oxygen to patients might be through oxygen mask, which does not involve any mechanical force for the oxygen. In contrast to ventilators and because of the thin wall of the lung sacs, oxygen masks help patients to get back to the normal path of breathing that is derived by negative partial pressure, and do not worsen the inflammation of the alveolar sacs of the lung. The process contains of two pathways where partial pressure is essential parameter that derives the diffused oxygen from high to low areas of pressure, initially between the alveolar and capillaries, and secondly between the capillaries and tissues. This causes the lung volume to be expanded due to the air that has delivered to it through pressure, which can be taken care of normally with the process of exhaling CO2 which is proportional to the output pressure. Oxygen in the alveolar can be adjusted accordingly to its partial pressure, which can be attained using a mass balance of oxygen in the alveolar. Using the alveolar gas equation, friction of inspired oxygen, which is more likely to be high in such treatment, is proportional to the standard pressure minus the fluid that might be in the way between the lung and the alveolar. Due to the pressure, all of which are flowing as inputs from the alveolar to the capillaries, while the opposite pressure of CO2, which diffuses from the capillaries into alveolar to be taken out of the body, is considered as an output. An alternative would be to decrease the friction inspiration of oxygen in the alveolar so that would result on less but effective delivered oxygen. The goal would be reached even if the patient stays in a healthcare for longer hours. Supplying the patient with more pressure to get extra oxygen would just work the other way and starts damaging the lung. Nevertheless, as many health professionals advise patients with COVID-19 to drink high amount of fluid, the equation of alveolar gas can be highly controlled to have a negative partial pressure of oxygen in the alveolar that is resulted from more water vaper that is associated with the air tract of the respiratory system.
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